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For RGCs, where oxidative phosphorylation plays a larger role in metabolic homeostasis than in Mller glia (Nsiah and Inman, 2022), the ketogenic diet promoted mitophagy beyond that which occurred with OHT

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This mechanism has validated GSSG's use across pharmaceutical applications targeting oxidative stress in hepatic disease, cardiovascular conditions, and neurodegenerative disorders, while simultaneously supporting its adoption in cosmetic and dietary supplement formulations